Connection strategies in neocortical networks

نویسندگان

  • Andreas Herzog
  • Karsten Kube
  • Bernd Michaelis
  • Ana D. de Lima
  • Thomas B. Voigt
چکیده

This study considers the impact of different connection strategies in developing neocortical networks. An adequate connectivity is a requisite for synaptogenesis and the development of synchronous oscillatory network activity during maturation of cortical networks. In a defined time window early in development neurites have to grow out and connect to other neurons. Based on morphological observations we postulate that the underlying mechanism differs from common strategies of unspecific global or small world strategies. We show here that a displaced local connection mode is a very effective approach to connect neurons with minimal costs.

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تاریخ انتشار 2006